Can Nutritional Status Predict Overall Survival in Patients with Advanced Non-Small Cell Lung Cancer?
| Autor: | Soo-Kyung Lee, Sehyun Kim, Young-Kwang Seo, Wankyu Eo, Bumsang Shim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Oncology Male Cancer Research medicine.medical_specialty Lung Neoplasms Medicine (miscellaneous) Nutritional Status Kaplan-Meier Estimate Body Mass Index 03 medical and health sciences 0302 clinical medicine Internal medicine Carcinoma Non-Small-Cell Lung Overall survival Medicine Humans In patient Lung cancer Aged Retrospective Studies 030109 nutrition & dietetics Nutrition and Dietetics business.industry Medical record Nutritional status Middle Aged medicine.disease Prognosis Antineoplastic Agents Phytogenic humanities respiratory tract diseases 030220 oncology & carcinogenesis Multivariate Analysis Female Non small cell business |
| Zdroj: | Nutrition and cancer. 71(7) |
| ISSN: | 1532-7914 |
| Popis: | Medical records of patients with advanced non-small cell lung cancer (NSCLC) were retrospectively reviewed to examine the prognostic impact of nutritional status on survival. Age, sex, body mass index (BMI), Eastern Cooperative Oncology Group Performance Status (ECOG-PS), histologic tumor type, pulmonary comorbidities, white blood cell (WBC) count, C-reactive protein (CRP) level, and prognostic nutritional index (PNI) were assessed. Overall survival was calculated using Kaplan-Meier analysis and compared using log-rank testing. Univariate and multivariate Cox regression model analyses were used to evaluate prognostic impact. Of the 183 enrolled patients, 166 had stage IV NSCLC; 70 had ECOG-PS scores of 2; and 129 had undergone prior anticancer therapy. Age ≥ 65 years, male sex, smoking, BMI21 kg/m |
| Databáze: | OpenAIRE |
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