Growth in young children with chronic renal failure
| Autor: | Maria Luisa Bianchi, Giorgio Ballabio, Roberto Rusconi, Fabiola Terzi, Aldo Claris-Appiani, Caterina Funari, M.P. Caraceni, Paolo Bini, Lucia Romeo |
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| Rok vydání: | 1989 |
| Předmět: |
Nephrology
Male medicine.medical_specialty Renal function Parathyroid hormone urologic and male genital diseases Nephropathy Blood Urea Nitrogen Internal medicine medicine Humans Child Blood urea nitrogen Growth Disorders Bone Development business.industry Hyperparathyroidism Infant Bone age medicine.disease Endocrinology Child Preschool Pediatrics Perinatology and Child Health Bone maturation Kidney Failure Chronic Female business Energy Intake Hormone |
| Zdroj: | Pediatric nephrology (Berlin, Germany). 3(3) |
| ISSN: | 0931-041X |
| Popis: | Statural growth and its relation to growth potential, renal function, blood urea nitrogen (BUN), mineral metabolism hormones and dietary intake were studied in 17 prepubertal children (aged 1.6–9.3 years) on conservative treatment for chronic renal failure due to tubulo-interstitial nephropathy. Statural growth (height SDS) was related to the degree of renal failure, was more retarded than ossification, and was independent of the chronological age of the patients. We observed that the lower the glomerular filtration rate (GRF), the lower was the growth potential (increased bone age/statural age ratio). Growth velocity may be normal regardless of statural and bone maturation delay and the degree of renal insufficiency. Impaired growth rate correlated with parathyroid hormone levels, caloric intake and increased blood urea nitrogen during the year of observation. These data show that comprehensive monitoring and suitable treatment must be performed in order to prevent growth retardation at any GFR level. |
| Databáze: | OpenAIRE |
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