Molecular Evidence of a Broad Range of Pathogenic Bacteria in Ctenocephalides spp.: Should We Re-Examine the Role of Fleas in the Transmission of Pathogens?
| Autor: | Stavroula Beleri, Charalambos Billinis, Georgios Dougas, Joseph Papaparaskevas, Eleni Patsoula, Athanassios Tsakris, Maria Linou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Bartonella Klebsiella pneumoniae animal diseases 030106 microbiology 030231 tropical medicine lcsh:Medicine medicine.disease_cause Enterococcus faecalis Microbiology 03 medical and health sciences 0302 clinical medicine medicine Microbiome Legionella bacteremia Ctenocephalides disease transmission metagenomics General Immunology and Microbiology biology flea infestations Transmission (medicine) lcsh:R Public Health Environmental and Occupational Health Pathogenic bacteria biology.organism_classification bacterial infections and mycoses Pseudomonas aeruginosa infectious Infectious Diseases Staphylococcus Bacteria |
| Zdroj: | Tropical Medicine and Infectious Disease, Vol 6, Iss 37, p 37 (2021) Tropical Medicine and Infectious Disease Volume 6 Issue 1 |
| ISSN: | 2414-6366 |
| Popis: | The internal microbiome of common cat and dog fleas was studied for DNA evidence of pathogenic bacteria. Fleas were grouped in pools by parasitized animal. DNA was extracted and investigated with 16S metagenomics for medically relevant (MR) bacteria, based on the definitions of the International Statistical Classification of Diseases and Related Health Problems (WHO). The MR bacterial species totaled 40, were found in 60% of flea-pools (N = 100), and included Acinetobacterbaumannii, Bacteroidesfragilis, Clostridiumperfringens, Enterococcusfaecalis, E. mundtii, Fusobacteriumnucleatum, Haemophilusaegyptius, Kingellakingae, Klebsiellapneumoniae, Leptotrichiabuccalis, L. hofstadii, Moraxellalacunata, Pasteurellamultocida, Propionibacteriumacnes, P. propionicum, Proteusmirabilis, Pseudomonasaeruginosa, Rickettsiaaustralis, R. hoogstraalii, Salmonellaenterica, and various Bartonella, Staphylococcus, and Streptococcus species. B. henselae (p = 0.004) and B. clarridgeiae (p = 0.006) occurred more frequently in fleas from cats, whereas Rickettsiahoogstraalii (p = 0.031) and Propionibacteriumacnes (p = 0.029) had a preference in fleas from stray animals. Most of the discovered MR species can form biofilm, and human exposure may theoretically occur through the flea-host interface. The fitness of these pathogenic bacteria to cause infection and the potential role of fleas in the transmission of a broad range of diseases should be further investigated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|