Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery

Autor: John-Kalle Länsberg, Andreas Herbst, Louise Ronnje, Olga Vikhareva, Stefan R. Hansson, Mehreen Zaigham
Rok vydání: 2020
Předmět:
Male
myalgia
Abdominal pain
Pediatrics
Case Report
Respiratory failure
Obesity
Maternal
Neonate
Pregnancy
Pregnancy Complications
Infectious
Lung
Liver Diseases
Obstetrics and Gynecology
Blood Coagulation Disorders
Virus
Liver
Gestation
Female
Partial Thromboplastin Time
Differential diagnosis
medicine.symptom
Coronavirus Infections
Infant
Premature
Adult
HELLP Syndrome
medicine.medical_specialty
Fever
Respiratory distress syndrome
HELLP syndrome
Nausea
Antithrombin III
Pneumonia
Viral
lcsh:Gynecology and obstetrics
Diagnosis
Differential
Fibrin Fibrinogen Degradation Products
Sepsis
Betacoronavirus
medicine
Humans
Mortality
Pandemics
lcsh:RG1-991
Sweden
Coagulation
Obstetric management
L-Lactate Dehydrogenase
Pandemic
Cesarean Section
Platelet Count
SARS-CoV-2
business.industry
Infant
Newborn
COVID-19
medicine.disease
Coronavirus
Susceptibility
Apgar Score
Morbidity
Tomography
X-Ray Computed
business
Zdroj: BMC Pregnancy and Childbirth, Vol 20, Iss 1, Pp 1-8 (2020)
BMC Pregnancy and Childbirth
DOI: 10.21203/rs.3.rs-31225/v1
Popis: Background It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exaggerate the course of the COVID-19 infection. Case presentation A 26-year old Somalian woman (G2P1) presented with a nine-day history of shortness of breath, dry cough, myalgia, nausea, abdominal pain and fever. A nasopharyngeal swab returned positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Her condition rapidly worsened leading to severe liver and coagulation impairment. An emergency Caesarean section was performed at gestational week 32 + 6 after which the patient made a rapid recovery. Severe COVID-19 promptly improved by the termination of the pregnancy or atypical HELLP (Hemolysis, Elevated Liver Enzymes and Low Platelet Count) exacerbated by concomitant COVID-19 infection could not be ruled out. There was no evidence of vertical transmission. Conclusions This case adds to the growing body of evidence which raises concerns about the possible negative maternal outcomes of COVID-19 infection during pregnancy and advocates for pregnant women to be recognized as a vulnerable group during the current pandemic.
Databáze: OpenAIRE
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