Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles
| Autor: | Sreedevi, Meesaraganda, Prasad, Aluru Raghavendra Guru, Spoorthy, Yadati Narasimha, Ravindranath, Lakshmana Rao Krishna Rao |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Advanced Pharmaceutical Bulletin, Vol 3, Iss 1, Pp 227-230 (2013) |
| ISSN: | 2251-7308 2228-5881 |
| Popis: | Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity. Advanced Pharmaceutical Bulletin; eISSN 2251-7308 |
| Databáze: | OpenAIRE |
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