The Enhancement of Chlortetracycline Activity Against Pasteurella multocida with Sodium Sulfate
| Autor: | L. E. Ousterhout, Keenum Rd, Bruins Hw, Stuart Ee |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Chlortetracycline
medicine.drug_class Sodium Pasteurella Infections Antibiotics Tetracycline antibiotics chemistry.chemical_element Calcium Microbiology chemistry.chemical_compound Sodium sulfate medicine Animals Pasteurella multocida Poultry Diseases biology Sulfates General Medicine medicine.disease biology.organism_classification Coccidiosis chemistry Animal Science and Zoology medicine.drug |
| Zdroj: | Poultry Science. 45:21-26 |
| ISSN: | 0032-5791 |
| DOI: | 10.3382/ps.0450021 |
| Popis: | INTRODUCTION IT IS known that the presence of calcium ions in the intestine interfere with the absorption of tetracycline antibiotics by the chicken (Price et al., 1958–1959). Thus, blood levels of tetracycline antibiotics can be increased by reducing the level of dietary calcium (Riser and Roberts, 1957), by using a relatively insoluble calcium source, e.g. CaSO4 (Pensack et al., 1959; Stokstad, 1959), or by adding an organic acid which binds Ca + + (Eisner et al., 1953; Gray et al., 1953; 1954). It has been shown that blood levels of antibiotic increased by such dietary modifications enhance the activity of the drug against coccidiosis (Peterson, 1958), C.R.D. (Peterson and Hendrix, 1959), Salmonella gallinarum (Kiser, 1959), and infectious synovitis (Shelton and Olson, 1958). Pensack et al. (1959) and Nelson and Peeler (1961) reported that the addition of sodium sulfate to feeds containing chlortetracycline increased blood levels of the antibiotic. Since … |
| Databáze: | OpenAIRE |
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