Initiating long-acting injectable antipsychotics during acute admission for patients with schizophrenia – A 3-year follow-up
| Autor: | Tzung-Jeng Hwang, Jia-Chi Shan, Chen-Chung Liu, Ming H. Hsieh, Chih-Min Liu, Chih-Lin Chiang, Shao-Chien Chen, Yi-Ling Chien |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male rehospitalization medicine.medical_specialty medicine.medical_treatment Taiwan Administration Oral Kaplan-Meier Estimate Patient Readmission compliance Injections Medication Adherence Oral administration Internal medicine Humans Medicine long-acting injectable antipsychotic Antipsychotic Psychiatry Survival analysis Retrospective Studies Medicine(all) lcsh:R5-920 business.industry Acute admission Retrospective cohort study General Medicine Middle Aged medicine.disease Confidence interval schizophrenia Long acting Schizophrenia Female lcsh:Medicine (General) business Antipsychotic Agents Follow-Up Studies |
| Zdroj: | Journal of the Formosan Medical Association, Vol 114, Iss 6, Pp 539-545 (2015) |
| ISSN: | 0929-6646 |
| DOI: | 10.1016/j.jfma.2013.01.004 |
| Popis: | Background/PurposeThe debate on whether long-acting injectable antipsychotic (LAIA) medication is superior to oral medication, in preventing rehospitalization of patients with schizophrenia, remains inconclusive. We compared rehospitalization rates over 3 years following discharge from an acute admission, in which patients either began using LAIAs regularly for the first time, or continued to use oral antipsychotics.MethodsA retrospective observational study of 92 inpatients with schizophrenia from a university-based medical center during 2004–2008. The primary outcome measure is the rehospitalization rates between groups, as estimated by Kaplan-Meier survival analysis.ResultsEighteen of 47 (38.3%) LAIA patients, and 16 of 45 (35.6%) oral medication patients were rehospitalized (average time to rehospitalization, 378 ± 262 vs. 378 ± 340 days; p = 0.997). The estimated cumulative rates of rehospitalization were similar between groups. The overall odds comparing the LAIA to the oral medication group were 1.085 ± 0.373 (95% confidence interval: 0.553–2.13, p = 0.813). Compared to the oral medication group, the LAIA group had fewer coded with sufficient previous treatment response (32% vs. 69%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|