A standard hemodialysis prescription to prevent osmotic demyelination in hyponatremic patients requiring dialysis

Autor: Neriman Sila Koc, Tolga Yildirim, Sinem Girgin, Ceren Onal, Yagmur Tahillioglu, Rahmi Yilmaz, Mustafa Arici, Bulent Altun, Yunus Erdem
Rok vydání: 2022
Předmět:
Zdroj: Therapeutic Apheresis and Dialysis. 26:1182-1186
ISSN: 1744-9987
1744-9979
DOI: 10.1111/1744-9987.13818
Popis: We aimed to investigate the effect of a standard hemodialysis prescription in hyponatremic patients requiring hemodialysis on the development of osmotic demyelination syndrome.Ninety-nine patients who were treated with hemodialysis for the first time and had a pre-dialysis sodium value of ≤125 meq/L included in the study. Standard hemodialysis treatment was applied to all patients. Biochemical data before, immediately after and 24 h after hemodialysis were recorded retrospectively. All patients followed up for 2 weeks and magnetic resonance imaging was performed in patients with neurological symptoms.Eight patients had a sodium increase of more than 12 meq/L at 24-h after hemodialysis. Although hyponatremia was corrected rapidly with hemodialysis, none of the 99 azotemic patients developed osmotic demyelination syndrome.We did not observe osmotic demyelination syndrome in hyponatremic patients with azotemia treated with standard protocol hemodialysis. However, caution should still be exercised in high-risk patients for osmotic demyelination.
Databáze: OpenAIRE
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