S4. Effect of AZD5363 on the expression of endogenous ER genes by qRT-PCR. from AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo

Autor: Lesley-Ann Martin, Mitch Dowsett, Barry R. Davies, Stephen Johnston, Gianmaria Liccardi, Aradhana Rani, Hayley Campbell, Urszula M. Polanska, Nikiana Simigdala, Aurélie Thuleau, Qiong Gao, Elisabetta Marangoni, Stephanie K. Guest, Sunil Pancholi, Ricardo Ribas
Rok vydání: 2023
DOI: 10.1158/1535-7163.22502728
Popis: Cells lines were treated with the combinations stated above for 24-hours, RNA was extracted and cDNA synthetised. mRNA analysis was performed by RT-qPCR using taqman oligos described in the material and methods. Error bars represent {plus minus} SEM. *p
Databáze: OpenAIRE