Physiological effects of increased tissue pressure
| Autor: | Frederick A. Matsen, C. A. Mowery, R. V. King, R. B. Krugmire, T. Roche |
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| Rok vydání: | 1979 |
| Předmět: |
Partial Pressure
Neural Conduction Models Biological Nerve conduction velocity pCO2 Pressure Medicine Teflon membrane Animals Orthopedics and Sports Medicine Argon business.industry Partial pressure Anatomy Carbon Dioxide Hindlimb Oxygen Regional Blood Flow Circulatory system Surgery Functional status Rabbits Tissue pressure business Biomedical engineering |
| Zdroj: | International orthopaedics. 3(3) |
| ISSN: | 0341-2695 |
| Popis: | The physiological effects of increased tissue pressure were studied using a model system in which known pressures were applied uniformly to the hindlimbs of rabbits for a period of 5 h. Muscle blood flow was monitored using a new argon washout technique. Muscle pO2, pCO2, and pAr were measured using a Teflon membrane catheter-mass spectrometer system. The myoneural conduction velocity served as a measure of the functional status of the limb. Higher tissue pressures led to successively greater compromise of muscle blood flow and pO2. Myoneural conduction velocity decreased significantly only when a pressure of 80 mm of mercury was applied, at which time muscle blood flow and pO2 were zero. These observations suggest that abnormalities of neuromuscular function are relatively late manifestations of a pressureinduced circulatory deficiency. |
| Databáze: | OpenAIRE |
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