Synthesis of YF3: Yb, Er upconverting nanofluorophores using chitosan and their cytotoxicity in MCF-7 cells
| Autor: | Sethuraman Gayathri, Annamraju Kasi Viswanath, M. Jeevan Kumar Reddy, Oriparambil Sivaraman Nirmal Ghosh, P. Sudhakara, A.M. Shanmugharaj |
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| Rok vydání: | 2015 |
| Předmět: |
Materials science
Biocompatibility Cell Survival Scanning electron microscope Analytical chemistry Energy-dispersive X-ray spectroscopy Nanoparticle Biochemistry Chitosan chemistry.chemical_compound X-Ray Diffraction Structural Biology Spectroscopy Fourier Transform Infrared Humans Hydrothermal synthesis Ytterbium Fourier transform infrared spectroscopy High-resolution transmission electron microscopy Molecular Biology Fluorescent Dyes Cell Death Spectrometry X-Ray Emission General Medicine chemistry Luminescent Measurements MCF-7 Cells Nanoparticles Erbium Nuclear chemistry |
| Zdroj: | International Journal of Biological Macromolecules. 72:1308-1312 |
| ISSN: | 0141-8130 |
| Popis: | In this work, we described one pot hydrothermal synthesis of surface modified water soluble YF3: Yb, Er upconverting nanofluorophores (UCNFs) using natural biopolymer chitosan. The obtained nanocrystals have undergone X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), high resolution transmission electron microscopy (HRTEM) and photoluminescence (PL) studies. The nanoparticles possess uniform particle size distribution with average size about 27 nm. The cytotoxicity results revealed that the chitosan capped nanoparticles exhibit excellent biocompatibility in human breast cancer cells. In conclusion, the water soluble chitosan capped YF3: Yb, Er nanoparticles could be used as a potential candidate in bio-imaging and therapeutic applications. |
| Databáze: | OpenAIRE |
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