Predictive value of monocytes and lymphocytes for short-term neutrophil changes in chemotherapy-induced severe neutropenia in solid tumors
| Autor: | Bu-hong Zheng, Liang Hong, Zhiyu Huang, Jinluan Li, Junxin Wu, Yunxia Huang |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutrophils medicine.medical_treatment Lymphocyte Antineoplastic Agents Neutropenia Logistic regression Gastroenterology Severity of Illness Index Monocytes 03 medical and health sciences Leukocyte Count 0302 clinical medicine Predictive Value of Tests Internal medicine Neoplasms medicine Cutoff Humans Platelet 030212 general & internal medicine Lymphocytes Chemotherapy-Induced Febrile Neutropenia Aged Retrospective Studies Chemotherapy Receiver operating characteristic business.industry Monocyte Middle Aged medicine.disease medicine.anatomical_structure Treatment Outcome Oncology 030220 oncology & carcinogenesis Female business |
| Zdroj: | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 28(3) |
| ISSN: | 1433-7339 |
| Popis: | To explore whether monocytes, lymphocytes, and platelets have a predictive value for short-term neutrophil changes in patients with severe neutropenia (SN) induced by chemotherapy. Complete blood counts (CBC) were collected from a total of 62 patients with chemotherapy-induced SN from December 2013 to March 2018. CBCs at intervals of 1 day, 2 days, 3 days, 4 days, and 5 days were recorded, and logistic regression analyses were performed to determine whether the monocyte percentage (MP), absolute monocyte count (AMC), lymphocyte percentage (LP), absolute lymphocyte count (ALC), or platelet count (PC) were correlated with short-term neutrophil changes. The areas under the receiver operating characteristic (ROC) curves (AUCs) were calculated for parameters with a P value |
| Databáze: | OpenAIRE |
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