Relationship Between Respiratory Muscle Strength and Lean Body Mass in Men With COPD
| Autor: | Masaharu Tsutsumi, Yoshihiro Nishimura, Tohru Tsunenari, Hiroyuki Nakata, Hitoshi Maeda, Mitsuhiro Yokoyama |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Spirometry medicine.medical_specialty Respiratory physiology Critical Care and Intensive Care Medicine Body Mass Index Pulmonary function testing Absorptiometry Photon Internal medicine medicine Respiratory muscle Humans Lung Diseases Obstructive Aged COPD medicine.diagnostic_test business.industry Body Weight Respiratory disease Middle Aged medicine.disease Body Height Respiratory Muscles Biomechanical Phenomena Surgery Endocrinology Body Composition Respiratory Mechanics Lean body mass Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | Chest. 107:1232-1236 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.107.5.1232 |
| Popis: | It has been suggested that low body weight may be associated with decreased respiratory muscle function in COPD, but the precise mechanism is not known. Since body compositional change inevitably accompanies body weight change, we decided to study the possible relationship between respiratory muscle strength and body composition in patients with COPD. We studied respiratory muscle strength, pulmonary function, and body composition in 24 Japanese male patients with COPD. Patients were divided into two groups according to their body weight (group A, body weight lower than 80% of ideal body weight vs group B, 80% or more) and a comparison was made together with age-matched controls (group C). Maximal inspiratory mouth pressure (PImax) and maximal expiratory mouth pressure (PEmax) were measured by a previously reported method. Body compositional analysis was performed using dual energy x-ray absorptiometry (DXA; Norland XR26). It showed significantly lower fat body mass (FAT), FAT/body weight%, and lean body mass (LEAN) in group A than those in group B. The PImax in group A was significantly lower than that in group B and C (44.2 +/- 13.8, 76.4 +/- 29.9, and 88.6 +/- 18.1 cm H2O, respectively). PEmax in group A was also significantly lower than that in group B and group C (61.9 +/- 20.1, 86.7 +/- 26.8, and 90.4 +/- 17.6 cm H2O, respectively). Both PImax and PEmax were significantly correlated with LEAN (r = 0.656, r = 0.591, p0.01, respectively) in patients with COPD. These results show that respiratory muscle strength is closely associated with body weight and lean body mass in patients with COPD. The present approach to compare respiratory muscle strength with lean body mass should be useful for studying the mechanism of respiratory muscle weakness in patients with COPD. |
| Databáze: | OpenAIRE |
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