Effects of intraoperative temperatures on postoperative infections in infants and neonates
| Autor: | Marjorie J. Arca, Ankur Datta, Sarah Walker, Ruchi Amin |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Hyperthermia Operating Rooms Blood transfusion medicine.drug_class medicine.medical_treatment Antibiotics Hypothermia Logistic regression Body Temperature 03 medical and health sciences 0302 clinical medicine Risk Factors 030225 pediatrics Humans Surgical Wound Infection Medicine Blood Transfusion Retrospective Studies Analysis of Variance Univariate analysis business.industry Infant Newborn Infant General Medicine Perioperative medicine.disease Logistic Models Surgical Procedures Operative 030220 oncology & carcinogenesis Anesthesia Pediatrics Perinatology and Child Health Female Surgery medicine.symptom business Surgical site infection |
| Zdroj: | Journal of Pediatric Surgery. 55:80-85 |
| ISSN: | 0022-3468 |
| Popis: | Background Perioperative hypothermia has been shown to increase surgical site infection (SSI) rates in adults. We sought to characterize whether intraoperative hypothermia or hyperthermia is associated with postoperative infections in infants. Methods We conducted a retrospective review of patients ≤ 6 months old who underwent surgical procedures from November 2013 to October 2015 at a Level I ACS Children's Surgical Center. The outcome was infections within 30 days after operation, with particular attention to SSI. Data obtained included weight and age at surgery, American Society of Anesthesiologists (ASA) physiologic status, wound class, case length, blood transfusion within 72 h of surgery, and administration of prophylactic antibiotics. Temperatures were classified as hypothermia (T Results The 885 patients had 25 SSIs (2.8%) and 11 nonsurgical site infections (1.2%). On univariate analysis, weight at surgery, higher ASA, perioperative transfusions, and longer case length were associated with higher rate of SSI. Higher median Thigh, higher median T low, and any hyperthermia were associated with higher rate of SSI. On multivariable logistic regression adjusted analyses, hyperthermia at any time during the case was associated with SSI (OR 3.47, [95% CI 1.34, 9.04], p = 0.011). Transfusions were also associated with higher SSI rates (OR 3.60 [95% CI, 1.28, 10.3], p = 0.016). Conclusions Intraoperative hyperthermia is associated with increased SSI rates in infants. Level of Evidence III. |
| Databáze: | OpenAIRE |
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