Role of LIF Cytokine and CD34 Angiogenesis Marker in Non-Developing Pregnancy
| Autor: | I. M. Kvetnoi, A. S. Dyatlova, V O Polyakova, E S Popravka, Yu. S. Krylova, N S Linkova |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Abortion Habitual Angiogenesis medicine.medical_treatment Physiology Gene Expression Inflammation Antigens CD34 Disease Endometrium Leukemia Inhibitory Factor General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans Embryo Implantation 030219 obstetrics & reproductive medicine Neovascularization Pathologic business.industry Age Factors General Medicine medicine.disease Prognosis Leukemia Pregnancy Trimester First 030104 developmental biology Cytokine medicine.anatomical_structure Case-Control Studies Immunology Etiology Female medicine.symptom business Biomarkers |
| Zdroj: | Bulletin of experimental biology and medicine. 163(6) |
| ISSN: | 1573-8221 |
| Popis: | The expression of cytokine LIF (leukemia inhibiting factor) in the endometrium of women of young reproductive age with non-developing pregnancy of unknown genesis is higher than in older women and women with infection-related miscarriages by 1.26 and 1.43 times, respectively. The expression of angiogenesis marker CD34 in the endometrium of young women with non-developing pregnancy of unknown origin is 1.59 times higher and in case of endometrial inflammation 1.31 times higher than in women of the older reproductive age with the same disease. Correlation between the endometrial expression of LIF and CD34 is detected in women of the younger reproductive age with non-developing pregnancy of unknown etiology. The expression of LIF and CD34 can be used for endometrial function evaluation in women of different age with first trimester non-developing pregnancy. |
| Databáze: | OpenAIRE |
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