Whole Genome Re-Sequencing of Three Domesticated Chicken Breeds
| Autor: | Bongjun Son, Dong-Yep Oh, Seunguk Lee, Sejong Oh, Seyoung Mun, Man Hwan Oh, Kyudong Han, Jae Jung Ha, JunKoo Yi |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Organic Anion Transporters Sodium-Independent Biology Genome 03 medical and health sciences Animals Domestication Gene Phylogeny Whole genome sequencing Genetics Genetic Variation Pigments Biological Feathers Breed White (mutation) 030104 developmental biology Gene Expression Regulation Genetic marker Feather visual_art visual_art.visual_art_medium Animal Science and Zoology Chickens Receptor Melanocortin Type 1 |
| Zdroj: | Zoological Science. 33:73 |
| ISSN: | 0289-0003 |
| DOI: | 10.2108/zs150071 |
| Popis: | Chicken is one of the most popular domesticated species worldwide, as it can serve an important role in agricultural as well as biomedical research fields. Because it inhabits almost every continent and presents diverse morphology and traits, the need of genetic markers for distinguishing each breed for various purposes has increased. The whole genome sequencing of three different breeds (White Leghorn, Korean domestic, and Araucana) that show similar coloring patterns, with the exception of the White Leghorn breed, have confirmed previously reported genomic alterations and identified many novel variants. Additionally, the Whole Genome Re-Sequencing (WGRS) approach identified an approximately 4 kb insert within SLCO1B3 responsible for blue egg shell color. Targeted investigation of pigment-related genes corroborated previously reported non-synonymous mutations, and provided deeper insight into chicken coloring, where not a single but a combination of non-synonymous mutations in the MC1R gene is likely to be responsible for altered feather coloring. |
| Databáze: | OpenAIRE |
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