Accuracy of syndromic management in targeting vaginal and cervical infections among symptomatic women of reproductive age attending primary care clinics in Dakar, Senegal
| Autor: | Amy Ndao Fall, Serge Covi-Alavo, Omar Gassama, Mohamed Diadhiou, Ibrahima Mall, Mame Diarra Ndiaye Gueye, Mamadou Saidou Barry, Awa Ba Diallo, Aissatou Gaye Diallo, Epainete Gawa, Jean Charles Moreau |
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| Rok vydání: | 2018 |
| Předmět: |
Vaginal discharge
Adult medicine.medical_specialty Cross-sectional study 030231 tropical medicine Gonorrhea medicine.disease_cause Risk Assessment 03 medical and health sciences Young Adult 0302 clinical medicine Trichomonas Vaginitis Anti-Infective Agents Positive predicative value medicine Gardnerella vaginalis Humans 030212 general & internal medicine business.industry Obstetrics Public Health Environmental and Occupational Health Candidiasis Vaginosis Bacterial Chlamydia Infections Middle Aged medicine.disease Senegal Infectious Diseases Cross-Sectional Studies Vaginal Discharge Parasitology Trichomonas vaginalis Female medicine.symptom Chlamydia trachomatis business |
| Zdroj: | Tropical medicineinternational health : TMIH. 23(5) |
| ISSN: | 1365-3156 |
| Popis: | OBJECTIVE To assess the effectiveness of the WHO syndromic algorithm in the management of vaginal discharge among women of reproductive age in Dakar. METHODS Cross-sectional study of consecutive female patients (aged 18-49 years) presenting with vaginal symptoms at six selected study sites in Dakar; of these, 276 patients were included in the analysis. Vaginal and cervical swab samples were collected and analysed to establish an aetiological diagnosis of any infection. Syndrome-based diagnosis was compared with the laboratory results to evaluate its accuracy based on sensitivity, specificity and positive and negative predictive values. The degree of agreement between the two approaches was assessed using the Cohen's kappa concordance analysis. RESULTS Overall prevalence of vaginal infections was 56.9% (157/276); 5.4% (15/276) of the patients had cervical infection. Using the syndromic approach, 51% of patients were correctly managed for Trichomonas vaginalis (TV)/Gardnerella vaginalis (GV); 61% for Candida albicans (CA) and 54% for Chlamydia trachomatis (CT)/Neisseria gonorrhoea (NG) infections. Consequently, 31% of patients with TV/GV, 51% with CA and 53% with CT/NG infections would have missed treatment. Further, the kappa value was |
| Databáze: | OpenAIRE |
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