Serotype distribution of Streptococcus pneumoniae causing invasive disease in the Republic of Ireland
| Autor: | I. Vickers, M.T. Cafferkey, M Fitzgerald, S. Murchan, Suzanne Cotter, D O'Flanagan, Hilary Humphreys |
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| Rok vydání: | 2010 |
| Předmět: |
Serotype
Adult Male Cefotaxime Heptavalent Pneumococcal Conjugate Vaccine Adolescent Epidemiology Population Microbial Sensitivity Tests Penicillins medicine.disease_cause Pneumococcal conjugate vaccine Pneumococcal Infections beta-Lactam Resistance Pneumococcal Vaccines Young Adult Streptococcus pneumoniae medicine Humans Serotyping education Child Aged Aged 80 and over education.field_of_study business.industry Vaccination Infant Newborn Infant Middle Aged Virology Anti-Bacterial Agents Bacterial Typing Techniques Penicillin Infectious Diseases Immunization Child Preschool business Ireland medicine.drug |
| Zdroj: | Epidemiology and infection. 139(5) |
| ISSN: | 1469-4409 |
| Popis: | SUMMARYThe 7-valent pneumococcal conjugate vaccine (PCV7) was included in the routine infant immunization schedule in Ireland in September 2008. We determined the serotype of 977 S. pneumoniae isolates causing invasive disease between 2000–2002 and 2007–2008, assessed for the presence of the recently described serotype 6C and determined the susceptibility of isolates during 2007–2008 to penicillin and cefotaxime. Serotype 14 was the most common serotype during both periods and 7·7% of isolates previously typed as serotype 6A were serotype 6C. During 2000–2002 and 2007–2008, PCV7 could potentially have prevented 85% and 74% of invasive pneumococcal disease in the target population (i.e. children aged |
| Databáze: | OpenAIRE |
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