Ocular morbidity associated with intravitreal triamcinolone acetonide
| Autor: | Richard Newsom, Aristides Konstantopoulos, A J Luff, C P R Williams |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Intraocular pressure Triamcinolone acetonide Eye Diseases genetic structures medicine.medical_treatment Anti-Inflammatory Agents Vitrectomy Exfoliation Syndrome Triamcinolone Acetonide Macular Edema Injections Endophthalmitis Retinal Diseases Ophthalmology medicine Humans Trabeculectomy Glucocorticoids Macular edema Intraocular Pressure Aged Retrospective Studies Aged 80 and over Diabetic Retinopathy business.industry Retinal Detachment Glaucoma Diabetic retinopathy Middle Aged Macular degeneration medicine.disease eye diseases Surgery Vitreous Body Female sense organs business medicine.drug |
| Zdroj: | Eye. 21:317-320 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/sj.eye.6702416 |
| Popis: | To report on the complications associated with the use of intravitreal triamcinolone acetonide (IVTA) in a tertiary referral hospital setting. A retrospective case series review of all IVTA injections carried out over a period of 30 months. One hundred and thirty IVTA injections were performed; nine with limited local follow-up were excluded. Thus, 121 injections (108 patients, 114 eyes) were included in the study. Triamcinolone (4 mg) was used in all cases. Indications were diabetic macular oedema (n=41 eyes), retinal vein occlusions (n=27), postoperative cystoid macular oedema (n=24), exudative age-related macular degeneration (n=16), and others (n=6). No intraoperative complications were recorded. Postoperative intraocular pressure (IOP) readings of 22, 28, 35, and 40 mmHg or higher were recorded in 46.5, 29.8, 12.3, and 7.9% of eyes, respectively. IOP elevation was treated with antiglaucoma medication in all but one eye (0.9%) that required trabeculectomy and one (0.9%) that required vitrectomy with cataract extraction for suspected phacoanaphylactic glaucoma. Two eyes (1.8%) developed retinal detachment; both had previously been treated for retinal breaks. One eye (0.9%) developed culture-positive endophthalmitis. Significant morbidity is associated with IVTA injection; clinicians should be aware when considering treatment options. |
| Databáze: | OpenAIRE |
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