Signal replication in a DNA nanostructure
| Autor: | Oscar Mendoza, Jean-Pierre Aimé, Said Houmadi, Juan Elezgaray |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Computer science
General Physics and Astronomy Nanotechnology 02 engineering and technology 010402 general chemistry Topology 01 natural sciences Signal Fluorescence Computers Molecular DNA origami Nanobiotechnology A-DNA Physical and Theoretical Chemistry Electronic circuit Fluorescent Dyes Nucleic Acid Hybridization DNA Equipment Design 021001 nanoscience & nanotechnology Replication (computing) 0104 chemical sciences Nanostructures Logic gate State (computer science) 0210 nano-technology |
| Zdroj: | The Journal of chemical physics. 146(2) |
| ISSN: | 1089-7690 |
| Popis: | Logic circuits based on DNA strand displacement reaction are the basic building blocks of future nanorobotic systems. The circuits tethered to DNA origami platforms present several advantages over solution-phase versions where couplings are always diffusion-limited. Here we consider a possible implementation of one of the basic operations needed in the design of these circuits, namely, signal replication. We show that with an appropriate preparation of the initial state, signal replication performs in a reproducible way. We also show the existence of side effects concomitant to the high effective concentrations in tethered circuits, such as slow leaky reactions and cross-activation. |
| Databáze: | OpenAIRE |
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