Bone Mineral Content in Chronic Renal Failure during Long-Term Treatment with 1α-Hydroxycholecalciferol
| Autor: | Klaus Olgaard, J. Ladefoged, S. Madsen |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Phosphatase Parathyroid hormone chemistry.chemical_element Calcium Bone and Bones Internal medicine Internal Medicine Vitamin D and neurology medicine Humans Aged Calcium metabolism Minerals Hydroxycholecalciferols business.industry Spectrophotometry Atomic Middle Aged Skeleton (computer programming) Demineralization Endocrinology chemistry Kidney Failure Chronic Bone mineral content Female business |
| Zdroj: | Europe PubMed Central |
| ISSN: | 0001-6101 |
| Popis: | Bone mineral content of the radius (BMC) has been measured by photonabsorptiometry in 22 adults with chronic renal failure before and after on an average 15.4 months of treatment with 1α-hydroxycholecaiciferol (1α-HCC). Identical measurements were performed in a control group comprising 26 uremic adults, who did not receive any vitamin D supplements during the study. The BMC was reduced and not significantly different in the two groups of uremic patients at the initial measurement. During treatment with 1α-HCC the BMC increased significantly in 3 patients, while the total group showed only a small (mean 0.7%), non-significant increase. In the control group the BMC decreased significantly in 4 patients, while the total group showed a non-significant decrease (mean 3.5%). However, a comparison of the BMC changes in the two groups revealed a significant difference (p |
| Databáze: | OpenAIRE |
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