Effectiveness of placental volume measured by virtual organ computer‐aided analysis in prediction of fetal hemoglobin Bart's disease in late first trimester

Autor: Phenphan Bootchaingam, Cholaros Charoenratana, Theera Tongsong, Suchaya Luewan
Rok vydání: 2021
Předmět:
Zdroj: Journal of Clinical Ultrasound. 49:533-537
ISSN: 1097-0096
0091-2751
DOI: 10.1002/jcu.23004
Popis: OBJECTIVE To evaluate the effectiveness of placental volume measured by virtual organ computer-aided analysis (VOCAL) at 12 to 14 weeks of gestation in predicting fetal hemoglobin (Hb) Bart's disease among pregnancies at risk. METHODS This study involves 3-dimensional ultrasound (3D-US) volume datasets derived from pregnancies at risk of fetal Hb Bart's disease at 12 to 14 weeks of pregnancy. VOCAL technique was used to measure and calculate placental volume by the authors, who did not know the fetal diagnosis. Placental thickness was also measured. The diagnostic values of placental volume and placental thickness in prediction of fetal Hb Bart's disease were calculated. RESULTS Sixty-five volume datasets, including 22 datasets of the affected fetuses and 43 unaffected fetuses, were included. The mean placental volume (±SD) of the affected cases was significantly higher than that of the unaffected ones, 85.35 ± 20.84 cm3 vs 52.24 ± 19.01 cm3 (Student's t test, P
Databáze: OpenAIRE