High frequency ultrasound as a selective advanced oxidation process to remove penicillinic antibiotics and eliminate its antimicrobial activity from water
| Autor: | Efraím A. Serna-Galvis, Oscar A. Flórez-Acosta, Ricardo A. Torres-Palma, Javier Silva-Agredo, Ana L. Giraldo-Aguirre |
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| Rok vydání: | 2016 |
| Předmět: |
Acoustics and Ultrasonics
medicine.drug_class Sonication Antibiotics Penicillins 02 engineering and technology 010501 environmental sciences 01 natural sciences Microbiology Sonochemistry Inorganic Chemistry medicine Chemical Engineering (miscellaneous) Environmental Chemistry Ultrasonics Radiology Nuclear Medicine and imaging 0105 earth and related environmental sciences Chemistry Organic Chemistry Advanced oxidation process 021001 nanoscience & nanotechnology Antimicrobial 6. Clean water Wastewater Photocatalysis Water treatment 0210 nano-technology Oxidation-Reduction Water Pollutants Chemical Nuclear chemistry |
| Zdroj: | Ultrasonics Sonochemistry. 31:276-283 |
| ISSN: | 1350-4177 |
| DOI: | 10.1016/j.ultsonch.2016.01.007 |
| Popis: | This work studies the sonochemical degradation of a penicillinic antibiotic (oxacillin) in simulated pharmaceutical wastewater. High frequency ultrasound was applied to water containing the antibiotic combined with mannitol or calcium carbonate. In the presence of additives, oxacillin was efficiently removed through sonochemical action. For comparative purposes, the photo-Fenton, TiO2 photocatalysis and electrochemical oxidation processes were also tested. Therefore, the evolution of the antibiotic and its associated antimicrobial activity (AA) were monitored. A high inhibition was found for the other three oxidation processes in the elimination of the antimicrobial activity caused by the additives; while for the ultrasonic treatment, a negligible effect was observed. The sonochemical process was able to completely degrade the antibiotic, generating solutions without AA. In fact, the elimination of antimicrobial activity showed an excellent performance adjusted to exponential kinetic-type decay. The main sonogenerated organic by-products were determined by means of HPLC-MS. Four intermediaries were identified and they have modified the penicillinic structure, which is the moiety responsible for the antimicrobial activity. Additionally, the possible oxacillin sonodegradation mechanism was proposed based on the evolution of the by-products and their chemical structure. Furthermore, the high-frequency ultrasound action over 120 min readily removed oxacillin and eliminated its antimicrobial activity. However, the pollutant was not mineralized even after a long period of ultrasonic irradiation (360 min). Interestingly, the previously sonicated water containing oxacillin and both additives was completely mineralized using non-adapted microorganisms from a municipal wastewater treatment plant. These results show that the sonochemical treatment transformed the initial pollutant into substances that are biotreatable with a typical aerobic biological system. |
| Databáze: | OpenAIRE |
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