'Sandstorm' image: bone scintigraphy in pulmonary alveolar microlithiasis

Autor: Ratimir Petrović, Gordana Horvatić Herceg, Irena Bračić, Davorin Herceg, Sanja Kusačić Kuna, Damir Dodig, Marta Koršić
Jazyk: angličtina
Rok vydání: 2009
Předmět:
DOI: 10.1007/s00259-009-1137-6
Popis: Pulmonary alveolar microlithiasis (PAM) is a rare idiopathic disorder, usually with familial association, leading to alveolar deposition of calcium phosphate microliths. A 48-year-old female patient was referred to our clinic for bone scintigraphy because of severe osteoporosis (L1–L4 T score was −3.5 ; serum calcium values and 24-h calciuria in normal range). Bone scintigraphy showed bilateral, intense pulmonary 99mTc- methylenediphosphonate uptake, which led us to clinical suspicion of PAM. The chest radiograph revealed extensive, bilateral micronodular sand-like appearance, predominantly in the lower lung fields. The diagnosis of PAM was confirmed by transbronchial lung biopsy. Although the bone scintigraphy finding is sometimes negative in the early stage of PAM , this imaging method could be very useful in the detection of PAM.
Databáze: OpenAIRE