Synthetic Strategies for the Preparation of Precursor Polymers and of Microcapsules Suitable for Cellular Entrapment by Polyelectrolyte Complexation of Those Polymersa
| Autor: | Xiaoyan Guo, Holly Alexander, Bin Huang, Zeng Wan, Wayne V. Moore, Zhizhong Meng, William T.K. Stevenson, Lei Zhou, Tania Dyakonov |
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| Rok vydání: | 2006 |
| Předmět: |
Models
Molecular chemistry.chemical_classification Polymers General Neuroscience Capsules Polymer General Biochemistry Genetics and Molecular Biology Polyelectrolyte Electrolytes Precursor polymer Entrapment Drug Delivery Systems Membrane History and Philosophy of Science chemistry Chemical engineering Mammalian cell Polymer chemistry Animals Humans |
| Zdroj: | Annals of the New York Academy of Sciences. 831:72-85 |
| ISSN: | 1749-6632 0077-8923 |
| Popis: | The production of microcapsules suitable for the entrapment of mammalian cell by means of polyelectrolyte complexation has, of a necessity, led to the development of novel strategies for the preparation of relatively bioinert polymers which complex efficiently under unique conditions to produce a mechanically resilient membrane with efficient transport properties. In this communication we relate a brief overview of capsule-membrane forming systems for the immunoisolation (or potential immunoisolation) of mammalian cells, which are based upon the complexation of polyelectrolyte (PE) polymers; with emphasis on precursor synthesis and relationships between precursor polymer structure and capsule membrane stability. |
| Databáze: | OpenAIRE |
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