Associação de metemoglobinemia e deficiência de glicose-6-fosfato desidrogenase em pacientes com malária tratados com primaquina
| Autor: | Wilson Duarte Alecrim, Marcos Antonio Ferreira da Rocha, Marli S. Santana, José Felipe Jardim Sardinha, Maria das Graças Costa Alecrim, Ana Ruth Lima Arcanjo |
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| Rok vydání: | 2007 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Primaquine Plasmodium vivax Methemoglobinemia Gastroenterology hemic and lymphatic diseases Internal medicine Deficiência da glicose-6-fosfato desidrogenase parasitic diseases medicine biology business.industry Malária Plasmodium falciparum medicine.disease biology.organism_classification Metemoglobinemia Dehydrogenase deficiency Diagnosis of malaria Infectious Diseases Clinical diagnosis Immunology Parasitology business Malaria medicine.drug |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical v.40 n.5 2007 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
| ISSN: | 0037-8682 |
| DOI: | 10.1590/s0037-86822007000500008 |
| Popis: | This study had the aim of investigating occurrences of methemoglobinemia among individuals with glucose-6-phosphate dehydrogenase deficiency during treatment for malaria infection using primaquine. Patients with a diagnosis of malaria caused by Plasmodium vivax or the V+F mixture (Plasmodium vivax + Plasmodium falciparum) were selected. Group 1 consisted of 74 individuals with a clinical diagnosis of methemoglobinemia and Group 2 consisted of 161 individuals without a clinical diagnosis of methemoglobinemia. The glucose-6-phosphate dehydrogenase deficiency rates (numbers of enzymopenic individuals) in Groups 1 and 2 were 51.3% (38) and 8.7% (14) respectively. These data demonstrated a statistically significant association with methemoglobinemia only among the individuals in Group 1 (p |
| Databáze: | OpenAIRE |
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