The role of interleukin-1ß and interleukin-33 in atopic dermatitis

Autor: Noha F. Ibrahim, Dina M. Metwally, Rania M. Abdel Hay, Laila A. Rashed
Rok vydání: 2013
Předmět:
Zdroj: Nasza Dermatologia Online, Vol 4, Iss 1, Pp 11-14 (2013)
ISSN: 2081-9390
DOI: 10.7241/ourd.20131.02
Popis: Introduction: Interleukin-1 super family is a group of cytokines that play a role in the regulation of immune and inflammatory responses. Interleukin-33 is a member of this family and is known to induce expression of the T helper2 cytokines that are important players in atopic dermatitis. Aim: To evaluate the expression of interleukins-1s and 33 as T helper2 cytokines inducers in patients with atopic dermatitis. Materials and Methods: This study included 20 atopic patients and 20 apparently healthy individuals serving as controls. Skin biopsies from all participants will be examined for detection of interleukins-1s and 33 by ELISA technique. Results: Both interleukins were statistically higher (P
Databáze: OpenAIRE