A 4.1-Kilodalton Polypeptide in the Cultural Supernatant of Mycoplasma fermentans Is One of the Substances Responsible for Induction of Interleukin-6 Production by Human Gingival Fibroblasts
| Autor: | Akira Hasebe, Tsuguo Watanabe, Ken-ichiro Shibata |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Immunology
Carbohydrates Gingiva Biology Microbiology Cell Line Kilodalton Bacterial Proteins medicine Animals Humans Mycoplasma fermentans Fibroblast Cells Cultured Host Response and Inflammation Interleukin-6 Tumor Necrosis Factor-alpha Interleukin Fibroblasts biology.organism_classification Molecular biology Culture Media Molecular Weight Infectious Diseases medicine.anatomical_structure Cell culture Polyclonal antibodies biology.protein Electrophoresis Polyacrylamide Gel Parasitology Tumor necrosis factor alpha Rabbits Antibody Peptides Interleukin-1 |
| Zdroj: | Infection and Immunity. 69:7173-7177 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.69.11.7173-7177.2001 |
| Popis: | The cultural supernatant of Mycoplasma fermentans induced interleukin-6 production by human gingival fibroblasts. The active entities were divided into hydrophilic and hydrophobic substances. In this study, we purified a 4.1-kilodalton polypeptide from the hydrophilic substances. It reacted with polyclonal antibodies to M. fermentans and activated human macrophages. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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