A multicenter clinical trial of recombinant human GM-CSF hydrogel for the treatment of deep second-degree burns

Autor:	Liping Zhang, Jiong Chen, Chunmao Han
Rok vydání:	2009
Předmět:	Adult Male medicine.medical_specialty Healing time Dermatology Hydrogel Polyethylene Glycol Dimethacrylate Double-Blind Method medicine Humans Second-Degree Burn Recombinant human GM-CSF Wound Healing Burn wound business.industry Significant difference Granulocyte-Macrophage Colony-Stimulating Factor Recombinant Proteins Surgery Clinical trial Treatment Outcome Female Dermatologic Agents Burns business Wound healing
Zdroj:	Wound Repair and Regeneration. 17:685-689
ISSN:	1524-475X 1067-1927
DOI:	10.1111/j.1524-475x.2009.00526.x
Popis:	Wound healing is a complex and dynamic biological process. The efficacy and safety of a recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) hydrogel to promote deep-second-degree burn wound healing is evaluated in this study. In this multicenter, randomized, double-blind, and placebo-controlled clinical trial, 90 patients with deep second-degree burns were randomly assigned into two groups. Complete healing time and percentage of wound healing at different time points were observed and side effects were recorded. A statistically significant difference was noted at each time point (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e67cb8ecae191b1a8e71dd0ca37cbc https://doi.org/10.1111/j.1524-475x.2009.00526.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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