Phylogenetic Analysis ofBacillus cereusIsolates from Severe Systemic Infections Using Multilocus Sequence Typing Scheme
| Autor: | Tadao Hasegawa, Megumi Oshimoto, Michio Ohta, Keiko Yamada, Akira Okamoto, Keizo Torii, Maria Vassileva, Norio Agata |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Lineage (evolution) Immunology Bacillus cereus Bacteremia Bacillaceae Infections Microbiology Phylogenetics Virology Databases Genetic Humans Clade Respiratory Tract Infections Phylogeny Aged Aged 80 and over Genetics biology Phylogenetic tree Sequence Analysis DNA Middle Aged biology.organism_classification Bacillus anthracis Cereus Child Preschool Multilocus sequence typing |
| Zdroj: | Microbiology and Immunology. 50:743-749 |
| ISSN: | 0385-5600 |
| DOI: | 10.1111/j.1348-0421.2006.tb03847.x |
| Popis: | Bacillus cereus strains from cases of severe or lethal systemic infections, including respiratory symptoms cases, were analyzed using multilocus sequence typing scheme of B. cereus MLST database. The isolates were evenly distributed between the two main clades, and 60% of them had allele profiles new to the database. Half of the collection's strains clustered in a lineage neighboring Bacillus anthracis phylogenetic origin. Strains from lethal cases with respiratory symptoms were allocated in both main clades. This is the first report of strains causing respiratory symptoms to be identified as genetically distant from B. anthracis. The phylogenetic location of the presented here strains was compared with all previously submitted to the database isolates from systemic infections, and were found to appear in the same clusters where clinical isolates from other studies had been assigned. It seems that the pathogenic strains are forming clusters on the phylogenetic tree. |
| Databáze: | OpenAIRE |
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