Geographical distribution and clinical relevance of non-tuberculous mycobacteria in Croatia
| Autor: | Ivan Sabol, Miroslav Samarzija, Ljiljana Zmak, Marko Jakopović, V. Katalinic Jankovic, Mateja Janković, J. van Ingen, Ante Marušić, Brigita Tićac, Mihaela Obrovac |
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| Rok vydání: | 2013 |
| Předmět: |
Lung Diseases
Male Veterinary medicine epidemiological study BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences Distribution (economics) Disease Cohort Studies 0302 clinical medicine atypical mycobacteria geographical diversity pulmonary NTM disease 030212 general & internal medicine Child Aged 80 and over education.field_of_study Incidence (epidemiology) BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti Incidence Nontuberculous Mycobacteria Middle Aged 3. Good health Infectious Diseases Child Preschool Female geographic locations Cohort study Pulmonary and Respiratory Medicine Adult Tuberculosis Adolescent Croatia Population Mycobacterium Infections Nontuberculous 03 medical and health sciences Young Adult Clinical Medical Sciences medicine Humans Clinical significance education Aged Retrospective Studies business.industry Poverty-related infectious diseases [N4i 3] Infant Retrospective cohort study medicine.disease bacterial infections and mycoses 030228 respiratory system business Demography |
| Zdroj: | The International Journal of Tuberculosis and Lung Disease Volume 17 Issue 6 International Journal of Tuberculosis and Lung Disease International Journal of Tuberculosis and Lung Disease, 17, 836-41 International Journal of Tuberculosis and Lung Disease, 17, 6, pp. 836-41 |
| ISSN: | 1815-7920 1027-3719 |
| DOI: | 10.5588/ijtld.12.0843 |
| Popis: | Item does not contain fulltext SETTING: The clinical relevance of non-tuberculous mycobacteria (NTM) in Croatia is unknown. OBJECTIVE: To estimate the isolation rate of NTM, record geographical differences and assess the burden of pulmonary NTM disease in Croatia. DESIGN: Nationwide retrospective cohort study of all Croatian residents with NTM isolated by culture in the period from 2006 to 2010. Microbiological criteria of the American Thoracic Society were used to establish a laboratory-based case definition of possible and probable NTM disease. RESULTS: Of 1187 individuals with pulmonary NTM isolates, 8.6% met the possible and 5.5% met the probable disease criteria. We estimated an annual incidence of probable pulmonary NTM disease of 0.23 per 100,000 population. This estimated annual incidence was 0.35/100,000 in the coastal region and 0.17/100,000 in the continental region. Species distribution differed between coastal and continental Croatia. NTM isolation frequency increased over the study period. CONCLUSION: Geography plays an important role in NTM species distribution and possible disease. The overall burden of NTM pulmonary disease in Croatia is still low compared to that of tuberculosis, but it is higher in the coastal region compared to the continental region. |
| Databáze: | OpenAIRE |
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