Five years of cardio-ankle vascular index (CAVI) and CAVI0: how close are we to a pressure-independent index of arterial stiffness?
| Autor: | Bart Spronck, Ashraf W. Khir, Tammo Delhaas, Koen D. Reesink, Alessandro Giudici |
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| Rok vydání: | 2021 |
| Předmět: |
pressure-dependency
2019-20 coronavirus outbreak medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Physiology pulse wave velocity Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BLOOD-PRESSURE EXERCISE Blood Pressure Pulse Wave Analysis AGE Vascular Stiffness DEPENDENCE Internal medicine ADOLESCENTS Internal Medicine medicine Humans Cardio-ankle vascular index CAVI(0) HEALTHY Pulse wave velocity White coat business.industry WHITE-COAT cardio-ankle vascular index CAVI0 medicine.disease arterial stiffness Blood pressure PULSE-WAVE VELOCITY Hypertension Cardiology Arterial stiffness LESSON Ankle Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Hypertension |
| ISSN: | 1473-5598 0263-6352 |
| DOI: | 10.1097/hjh.0000000000002928 |
| Popis: | Copyright © 2021 The Author(s). Pulse wave velocity, a common metric of arterial stiffness, is an established predictor for cardiovascular events and mortality. However, its intrinsic pressure-dependency complicates the discrimination of acute and chronic impacts of increased blood pressure on arterial stiffness. Cardio-ankle vascular index (CAVI) represented a significant step towards the development of a pressure-independent arterial stiffness metric. However, some potential limitations of CAVI might render this arterial stiffness metric less pressure-independent than originally thought. For this reason, we later introduced CAVI0. Nevertheless, advantages of one approach over the other are left debated. This review aims to shed light on the pressure (in)dependency of both CAVI and CAVI0. By critically reviewing results from studies reporting both CAVI and CAVI0 and using simple analytical methods, we show that CAVI0 may enhance the pressure-independent assessment of arterial stiffness, especially in the presence of large inter-individual differences in blood pressure. European Union’s Horizon 2020 Research and Innovation program (grant 793805 to B.S.). |
| Databáze: | OpenAIRE |
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