Omega-3 fatty acids plus vitamin for women with gestational diabetes or prediabetes: a meta-analysis of randomized controlled studies
| Autor: | Peijun Yan, Chunxia Jiang, Pan Chen, Yong Xu, Muhu Chen, Chenlin Gao, Lan Jiang |
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| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
Vitamin medicine.medical_specialty endocrine system diseases 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Controlled studies Gastroenterology Fetal Macrosomia law.invention Prediabetic State 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Randomized controlled trial Pregnancy law Internal medicine Fatty Acids Omega-3 medicine Vitamin D and neurology Humans Vitamin E Prediabetes Vitamin D Triglycerides business.industry Infant Newborn nutritional and metabolic diseases Obstetrics and Gynecology Cholesterol LDL Vitamins medicine.disease Gestational diabetes Diabetes Gestational chemistry Meta-analysis Dietary Supplements Pediatrics Perinatology and Child Health Premature Birth Female business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 35:3135-3142 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.1080/14767058.2020.1814239 |
| Popis: | Omega-3 fatty acids plus vitamin (e.g. vitamin D and E) may be beneficial to treat gestational diabetes mellitus (GDM), and we aimed to study the influence of omega-3 fatty acids plus vitamin versus placebo on the treatment efficacy of GDM.We searched the databases including PubMed, Embase, and the Cochrane Central Register of Controlled Trials, and randomized controlled trials (RCTs) assessing the influence of omega-3 fatty acids and vitamins combination supplementation versus placebo on metabolic status of GDM were included.Five RCTs were included in the meta-analysis. Compared with control intervention for women with GDM or prediabetes, omega-3 fatty acids plus vitamin substantially reduced fasting plasma glucose (FPG, mean difference [MD] = -11.25; 95% confidence intervals [CI] = -13.73 to -8.77;The supplementation of omega-3 fatty acids in combination with vitamin D or E can improve glycemic control, alleviate oxidative stress, and reduce triglycerides, but had no effects on total cholesterol, preterm delivery or macrosomia4000 g in women with GDM or prediabetes. |
| Databáze: | OpenAIRE |
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