Acute cerebral dysfunction in diabetic ketoacidosis: Survival followed by panhypopituitarism

Autor: Thomas J. Reagan, T. Yanagihara, Edward G. Lufkin, David H. Doan
Rok vydání: 1977
Předmět:
Zdroj: Metabolism. 26:363-369
ISSN: 0026-0495
DOI: 10.1016/0026-0495(77)90103-2
Popis: We report a unique case of a 15-yr-old diabetic patient who survived ketoacidosis complicated by acute severe encephalopathy, hypopituitarism, and optic atrophy. We reviewed our 25-yr experience with fatal diabetic ketoacidosis; three additional cases resembled the “cerebral edema” syndrome. We observed that (1) cerebral edema is not often documented in this syndrome, (2) the cause of the acute neuronal disturbance in these patients may be hypoxic, with cerebral edema a secondary development, and (3) development of encephalopathy was probably unrelated to overvigorous correction of acidosis and hyperglycemia in our cases.
Databáze: OpenAIRE