A Controlled Trial of Single Dose lntravesical Adriamycin in Superficial Bladder Tumours
| Autor: | R. G. Choa, N. A. Green, C. G. C. Gaches, M. H. Ashken, Paul Abrams |
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| Rok vydání: | 1981 |
| Předmět: |
Male
medicine.medical_specialty Adjuvant chemotherapy Urology medicine.medical_treatment Drug Administration Schedule law.invention Resection Randomized controlled trial law polycyclic compounds medicine Humans Saline Aged Clinical Trials as Topic Papilloma medicine.diagnostic_test business.industry Middle Aged Endoscopy Surgery Tumor recurrence carbohydrates (lipids) Urinary Bladder Neoplasms Doxorubicin Female Neoplasm Recurrence Local business |
| Zdroj: | British Journal of Urology. 53:585-587 |
| ISSN: | 1464-410X 0007-1331 |
| DOI: | 10.1111/j.1464-410x.1981.tb03266.x |
| Popis: | Summary— Sixty patients with recurrent superficial bladder tumours (Ta or T1) entered an open controlled trial of single dose Adriamycin. After transurethral resection of tumour recurrences, patients were alternately allocated to the control group or to the Adriamycin group, who received an instillation of 50 mg of Adriamycin in 50 ml of saline for 30 min. Six months later all patients were readmitted for endoscopy. In the Adriamycin group significantly more patients showed a decrease in the number of recurrent papillomas (72%) than in the control group (39%). This study shows that the use of adjuvant chemotherapy in the form of single dose Adriamycin is effective in reducing tumour recurrence. |
| Databáze: | OpenAIRE |
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