OXIDATIVE STRESS AND ANTI OXIDANTS STATUS IN PELLAGRA
| Autor: | Bandi Hari Krishna, Natham Mallikarjuna Reddy, Masthan Saheb, Desireddy Neelima |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Antioxidant medicine.medical_treatment Physiology lcsh:Medicine Disease medicine.disease_cause Lipid peroxidation chemistry.chemical_compound Pellagra Malondialdehyde Redox ratio Medicine Total anti oxidant status lcsh:R5-920 business.industry lcsh:R medicine.disease Obesity chemistry business lcsh:Medicine (General) Oxidative stress |
| Zdroj: | International Journal of Medical Research and Health Sciences, Vol 4, Iss 4, Pp 786-788 (2015) |
| ISSN: | 2319-5886 |
| Popis: | Background and objectives: Pellagra was vanished from most parts of the world where it was formerly present due to its dietary modification. However, it is still encountered among the jowar eating populations of India. The information about the role of oxidative stress in pellagra was not established. Therefore, in this study we assessed the oxidative stress status by using malondialdehyde (MDA), total anti oxidant status (TAOS) and redox ratio (RER) in clinically diagnosed pellagra patients. Materials and methods: Clinically diagnosed pellagra patients aged between 18 to 40 years, both male and females were recruited (n=78) from department of Dermatology. Age and gender matched controls (n=78) were recruited from the student and residents of the hospital. Malondialdehyde (MDA) is a marker of lipid peroxidation, Total Anti Oxidant Status (TAOS) and Redox Ratio (RER) markers were assessed by using commercially available kits. Results: There were no significant differences in the anthropometric parameters. However, the oxidative stress markers MDA (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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