Not a Usual Suspect; Rabeprazole Therapy Presenting as a Severe Neuropsychiatric Illness: Case Report
| Autor: | Myron D. Almond, Christopher A. Alfonzo, William V. Bobo |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Nosology medicine.medical_specialty medicine.drug_class Rabeprazole Proton-pump inhibitor 030204 cardiovascular system & hematology Neuropsychiatry Severity of Illness Index 030226 pharmacology & pharmacy 2-Pyridinylmethylsulfinylbenzimidazoles Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Humans Medicine Spectrum disorder Young adult Somatoform Disorders Adverse effect Intensive care medicine Psychiatry business.industry Mental Disorders Brain Proton-Translocating ATPases Psychiatry and Mental health Tolerability Gastroesophageal Reflux Benzimidazoles business Omeprazole medicine.drug |
| Zdroj: | The International Journal of Psychiatry in Medicine. 33:311-315 |
| ISSN: | 1541-3527 0091-2174 |
| DOI: | 10.2190/kx4x-ufk5-60kl-wd2g |
| Popis: | We report the case of a patient who, as a result of exposure to the proton pump inhibitor rabeprazole, developed a severe and disabling admixture of neuropsychiatric symptoms. Because of its widely appreciated placebo-like side effect profile, rabeprazole was never suspected as being the cause of his symptoms. Instead, a somatoform spectrum disorder was assigned based on the patient's atypical symptom presentation, progressive course, subjective psychological distress, intemperate consumption of healthcare resources over a relatively brief period of time and lack of any medical explanation for his symptoms at that time, despite exhaustive laboratory and radiologic work-ups. This case report reinforces the notion that even a medication such as rabeprazole, with an established safety and tolerability profile, may be associated with side effects severe enough to mimic disabling neuropsychiatric illness. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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