Pulmonary Complications in Hematopoietic Stem Cell Transplant Recipients—A Clinician Primer
| Autor: | Seth Kligerman, Catriona Jamieson, Erica Lin, Anna Astashchanka, Joseph Ryan, Jisha Joshua, Jess Mandel, Brandon Nokes, Atul Malhotra |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Antibiotics IPS bronchiolitis obliterans syndrome Review 03 medical and health sciences 0302 clinical medicine PERDS medicine Intensive care medicine post-HSCT business.industry DAH Hematopoietic stem cell General Medicine medicine.anatomical_structure surgical procedures operative 030220 oncology & carcinogenesis Medicine Histopathology Primer (molecular biology) Presentation (obstetrics) business Healthcare providers 030215 immunology |
| Zdroj: | Journal of Clinical Medicine Journal of Clinical Medicine, Vol 10, Iss 3227, p 3227 (2021) |
| ISSN: | 2077-0383 |
| Popis: | Hematopoietic stem cell transplants (HSCT) are becoming more widespread as a result of optimization of conditioning regimens and prevention of short-term complications with prophylactic antibiotics and antifungals. However, pulmonary complications post-HSCT remain a leading cause of morbidity and mortality and are a challenge to clinicians in both diagnosis and treatment. This comprehensive review provides a primer for non-pulmonary healthcare providers, synthesizing the current evidence behind common infectious and non-infectious post-transplant pulmonary complications based on time (peri-engraftment, early post-transplantation, and late post-transplantation). Utilizing the combination of timing of presentation, clinical symptoms, histopathology, and radiographic findings should increase rates of early diagnosis, treatment, and prognostication of these severe illness states. |
| Databáze: | OpenAIRE |
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