| Autor: |
Marion Ciancia, Monika Rataj-Baniowska, Nicolas Zinter, Vito Antonio Baldassarro, Valérie Fraulob, Anne-Laure Charles, Rosana Alvarez, Shin-ichi Muramatsu, Angel R. de Lera, Bernard Geny, Pascal Dollé, Anna Niewiadomska-Cimicka, Wojciech Krężel |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Progress in neurobiology. 212 |
| ISSN: |
1873-5118 |
| Popis: |
Retinoic acid is a powerful regulator of brain development, however its postnatal functions only start to be elucidated. We show that retinoic acid receptor beta (RARβ), is involved in neuroprotection of striatopallidal medium spiny neurons (spMSNs), the cell type affected in different neuropsychiatric disorders and particularly prone to degenerate in Huntington disease (HD). Accordingly, the number of spMSNs was reduced in the striatum of adult Rarβ |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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