Metabolism and health effects of phyto-estrogens
| Autor: | Mengmeng Xing, Shaoping Nie, Mingyong Xie, Xiao-Juan Hu, Qixing Nie, Jielun Hu |
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| Rok vydání: | 2015 |
| Předmět: |
Male
0301 basic medicine Heart disease Osteoporosis Phytoestrogens Endocrine Disruptors Bioinformatics Industrial and Manufacturing Engineering 03 medical and health sciences 0302 clinical medicine Breast cancer Animals Humans Endocrine system Medicine Adverse effect business.industry Menopausal Syndrome Estrogens General Medicine medicine.disease Menopause 030104 developmental biology 030220 oncology & carcinogenesis Female Plant Preparations business hormones hormone substitutes and hormone antagonists Food Science Hormone |
| Zdroj: | Critical Reviews in Food Science and Nutrition. 57:2432-2454 |
| ISSN: | 1549-7852 1040-8398 |
| DOI: | 10.1080/10408398.2015.1077194 |
| Popis: | Phyto-estrogens are plant-derived compounds that can exert various estrogenic and anti-estrogenic effects, and are usually used as a natural alternative to estrogen replacement due to their health benefits, including a lowered risk of osteoporosis, heart disease, breast cancer, and menopausal symptoms. Phyto-estrogens are also considered as endocrine disruptors due to their structure similar to human female hormone 17-β oestradiol. However, the issue of whether phyto-estrogens are beneficial or harmful to human health remains unknown, as this may depend on the dose, form, level and duration of administration of phyto-estrogens, and influence by genetics, metabolism, gut physiology, age, diet, and the health status of individuals. Clarification on this issue is necessary for the sake of their two-side effects on human health and rapidly increasing global consumption of phyto-estrogens. This review mainly includes the metabolism of phyto-estrogens and weighs the evidence for and against the purported health benefits and adverse effects of phyto-estrogens. |
| Databáze: | OpenAIRE |
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