Prognostic value of fatty acid imaging in patients with angina pectoris without prior myocardial infarction: comparison with stress thallium imaging
| Autor: | Tomoaki Nakata, Kazuaki Shimamoto, Masaru Shimazaki, Takashi Sakamoto, Kazuaki Yamauchi, Koichi Morita, Takayuki Matsuki, Michihiro Iwata, Atsushi Doi, Hiroshi Takahashi, Nagara Tamaki |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Myocardial Infarction chemistry.chemical_element Risk Assessment Sensitivity and Specificity Disease-Free Survival Angina Pectoris Angina Iodine Radioisotopes Myocardial perfusion imaging Japan Risk Factors Internal medicine Diabetes mellitus medicine Humans Radiology Nuclear Medicine and imaging Myocardial infarction Thallium Radionuclide Imaging Aged chemistry.chemical_classification Ejection fraction medicine.diagnostic_test business.industry Iodobenzenes Fatty Acids Fatty acid Reproducibility of Results General Medicine Middle Aged medicine.disease Prognosis chemistry Heart failure Cardiology Exercise Test Female Radiopharmaceuticals business |
| Zdroj: | European journal of nuclear medicine and molecular imaging. 31(12) |
| ISSN: | 1619-7070 |
| Popis: | A fatty acid analogue, 123I-labelled β-methyl iodophenyl pentadecanoic acid (BMIPP), has been used to identify ischaemic and metabolically impaired myocardium. However, the prognostic value of BMIPP imaging, particularly in relation to stress myocardial perfusion imaging, remains unclear. Data from 167 consecutive patients with angina pectoris but without prior myocardial infarction (MI) who had undergone both BMIPP and stress 201Tl (sTL) imaging were analysed. Tracer uptake was graded using a 13-segment, 4-point scoring model. Patients were followed up for 48 months with primary end points (cardiac death, non-fatal MI) as hard cardiac events and with secondary end points (late revascularisation, recurrent angina and heart failure) as soft events. For overall cardiac events (5 hard and 29 soft events), Kaplan-Meier analysis revealed significantly lower event rates in subgroups with normal BMIPP uptake, a summed difference score of sTL (SDS) of |
| Databáze: | OpenAIRE |
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