Trends in Myocardial Infarction Rates and Case Fatality by Anatomical Location in Four United States Communities, 1987 to 2008 (from the Atherosclerosis Risk in Communities Study)

Autor: Wayne D. Rosamond, Lisa M. Wruck, Daichi Shimbo, Jonathan D. Newman, Laura R. Loehr, JoEllyn M. Abraham, Aaron R. Folsom, Xiaoxi Liu, Chris Baggett, Richard S. Crow
Jazyk: angličtina
Rok vydání: 2013
Předmět:
DOI: 10.17615/c90x-er05
Popis: Although the incidence of and mortality following ST-segment elevation myocardial infarction (STEMI) is decreasing, time-trends in anatomical location of STEMI and associated short-term prognosis have not been examined in a population-based community study. We determined 22-year trends in age- and race-adjusted, gender-specific incidence rates and 28-day case fatality of hospitalized STEMI by anatomic infarct location among a stratified random sample of 35-74 year old residents of four communities in the Atherosclerosis Risk in Communities (ARIC) study. STEMI infarct location was assessed by 12-lead electrocardiograms (ECG) from the hospital record, and was coded as anterior, inferior, lateral and multi-location STEMI using the Minnesota Code. Between 1987 and 2008, a total of 4,845 patients had an incident STEMI; 37.2% were inferior STEMI; 32.8% were anterior; 16.8% occurred in multiple infarct locations and 13.2% were lateral STEMI. For inferior, anterior and lateral STEMI in both men and women, significant declines were observed in the age-adjusted annual incidence rate and the associated 28-day case fatality. In contrast, for STEMI in multiple infarct locations, neither the annual incidence rate nor the 28-day case fatality changed over time. The age- and race-adjusted annual incidence rate and associated 28-day case fatality of STEMI in anterior, inferior and lateral infarct locations declined over 22 years of surveillance; however, no decline was observed for STEMI in multiple infarct locations. In conclusion, our findings suggest there is room for improvement in the care of patients with multi-location STEMI.
Databáze: OpenAIRE