Putting together an MHC class I molecule
Autor: | Hidde L. Ploegh, Marie-Jose Bijlmakers |
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Rok vydání: | 1993 |
Předmět: |
Protein Folding
Chaperonins CD74 Protein Conformation Immunology Computational biology Human leukocyte antigen Protein Sorting Signals Major histocompatibility complex Mice Gene Frequency HLA-A2 Antigen MHC class I Animals Humans Immunology and Allergy Genetics biology Antigen processing Histocompatibility Antigens Class I Proteins Transporter associated with antigen processing MHC restriction Folding (chemistry) biology.protein Peptides |
Zdroj: | Current Opinion in Immunology. 5:21-26 |
ISSN: | 0952-7915 |
Popis: | Formation of MHC class I complexes involves proper folding of the subunits, their assembly and interaction with peptides. Several proteins contributing to this process have been described, but a number of questions remain, in particular those concerning early folding steps and interactions with peptide in the course of biosynthesis. |
Databáze: | OpenAIRE |
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