Asymmetric desymmetrization of meso-vic-diols by carbamoylation catalyzed with a chiral Cu(II) complex
Autor: | Osamu Onomura, Yoshihiro Matsumura, Masaru Mitsuda, Nobuto Ushijima, Kazuya Matsumoto, Yosuke Demizu |
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Jazyk: | angličtina |
Rok vydání: | 2006 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 47(48):8453-8456 |
ISSN: | 0040-4039 |
Popis: | Asymmetric desymmetrization of meso-vic-diols was achieved by carbamoylation in the presence of copper triflate and (S,S)-Ph-BOX as a catalyst without any use of bases. The method was successfully applied to asymmetric desymmetrization of five- to eight-membered cyclic meso-vic-diols in high enantioselectivity with up to 93% ee. Tetrahedron Letters 47(48) pp.8453-8456, 2006 |
Databáze: | OpenAIRE |
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