Empirical antibiotic therapy for pneumonia in intensive care units: a multicentre, retrospective analysis of potentially pathogenic microorganisms identified by endotracheal aspirates cultures
| Autor: | W. N. K. A. van Mook, H. Van Dessel, H. L. Duong, Johannes B. J. Scholte, R. van der Horst, Catharina F. M. Linssen, Dennis C J J Bergmans, Paul Roekaerts, Paul H. M. Savelkoul |
|---|---|
| Přispěvatelé: | Medische Microbiologie, Anesthesiologie, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, RS: CAPHRI School for Public Health and Primary Care, Intensive Care, RS: CAPHRI - R4 - Health Inequities and Societal Participation |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Microbiology (medical) Pediatrics medicine.medical_specialty Time Factors FLUOROQUINOLONES EARLY-ONSET Microbial Sensitivity Tests GUIDELINES Tazobactam law.invention law Clavulanic acid Intensive care medicine Pneumonia Bacterial Humans STENOTROPHOMONAS-MALTOPHILIA Hospitals Teaching Aged Netherlands Retrospective Studies SURVEILLANCE CULTURES RISK VENTILATOR-ASSOCIATED PNEUMONIA Bacteria business.industry Ventilator-associated pneumonia CONSUMPTION General Medicine Amoxicillin Middle Aged medicine.disease Intensive care unit Anti-Bacterial Agents Trachea Pneumonia Intensive Care Units ACQUIRED PNEUMONIA Infectious Diseases Original Article Female business RESISTANCE medicine.drug Piperacillin |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases, 34(11), 2295-2305. Springer, Cham European Journal of Clinical Microbiology & Infectious Diseases |
| ISSN: | 0934-9723 |
| DOI: | 10.1007/s10096-015-2482-y |
| Popis: | The purpose of this investigation was to explore the presumed relationship between the days of hospitalisation and microorganisms identified by endotracheal aspirate cultures in relation to adequate empirical treatment strategies of pneumonia in the intensive care unit (ICU). All potentially pathogenic microorganisms identified by (surveillance) cultures of endotracheal aspirates obtained in the ICUs of two Dutch teaching hospitals in 2007 and 2012 were retrospectively collected and analysed. Antibiotic susceptibilities to 11 antibiotics were calculated for several time points (days or weeks) after hospital admission and expressed per patient-day. In total, 4184 potentially pathogenic microorganisms identified in 782 patients were analysed. Prevalence of the classic early-onset pneumonia-causing microorganisms decreased from 55 % on the first four days to 34 % on days 4–6 after hospital admission (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink