Will the Use of Lyophilized Citrate Tubes Lead to the Over-Diagnosis of Diabetes in Pregnancy?
| Autor: | Rebekah Jane Carey, Chris Frampton, Christopher M. Florkowski, Helen Lunt, Martin J. Churcher, Ruth C. E. Hughes, Helen F. Heenan |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Pregnancy endocrine system diseases Obstetrics business.industry Diabetes in pregnancy nutritional and metabolic diseases 030209 endocrinology & metabolism General Medicine Gold standard (test) 030204 cardiovascular system & hematology Phlebotomy medicine.disease Gestational diabetes 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine Diabetes mellitus medicine Lead (electronics) business Over diagnosis |
| Zdroj: | The journal of applied laboratory medicine. 1(5) |
| ISSN: | 2576-9456 |
| Popis: | The International Association of Diabetes and Pregnancy Study Group (IADSPG)1 plasma glucose concentration thresholds used for diagnosing gestational diabetes mellitus (GDM) (1) are based on the risk of an adverse fetal outcome according to the landmark Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study. The HAPO study used research-grade methodology to minimize preanalytical glucose loss after an oral glucose tolerance test (OGTT); thus, samples were cooled and plasma separated shortly after phlebotomy (1). This sample processing is the gold standard for GDM-related studies of plasma glucose. A diagnosis of GDM using IADSPG criteria has been shown to be sensitive to bias in plasma glucose measurement; for … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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