Alterations in adrenal cortical function in fasting obese subjects
| Autor: | Donald E. Maynard, Stephen H. Schachner, Ralph G. Wieland, George J. Hamwi, Fred A. Kruger |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
Cortisol secretion
medicine.medical_specialty Hydrocortisone Endocrinology Diabetes and Metabolism Urinary system Renal function Urine In Vitro Techniques Excretion Endocrinology Adrenal Cortex Hormones Internal medicine Adrenal Glands medicine Humans Obesity Starvation 17-Hydroxycorticosteroids business.industry Fasting medicine.disease 17-Ketosteroids medicine.symptom business medicine.drug Glomerular Filtration Rate |
| Zdroj: | Metabolism: clinical and experimental. 14(10) |
| ISSN: | 0026-0495 |
| Popis: | The effect of short periods of starvation on adrenal function was evaluated in a group of obese females. Normal plasma cortisol levels were maintained during the fast period, while urinary excretion of 17-hydroxycorticoids, 17-ketosteroids, and unconjugated 11-hydroxycorticoids fell. Evidence indicates that a reduction of cortisol secretion occurs during brief periods of fasting. In addition, the measurement of urinary 11-hydroxycorticoids may be a rapid and efficient method for differentiating exogenous obesity from Cushing's syndrome. |
| Databáze: | OpenAIRE |
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