Superficial spreading melanoma: an analysis of 97 702 cases using the SEER database
| Autor: | Robert A. Schwartz, Hee Jin Kim, Parmvir Singh |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Skin Neoplasms Population Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Internal medicine Epidemiology medicine Surveillance Epidemiology and End Results Humans education Melanoma Survival analysis Retrospective Studies education.field_of_study business.industry Incidence (epidemiology) Hazard ratio Retrospective cohort study Middle Aged medicine.disease Survival Analysis Superficial spreading melanoma Oncology 030220 oncology & carcinogenesis Disease Progression Female business SEER Program |
| Zdroj: | Melanoma Research. 26:395-400 |
| ISSN: | 0960-8931 |
| DOI: | 10.1097/cmr.0000000000000245 |
| Popis: | Superficial spreading melanoma (SSM) is the most common type of melanoma. Large, population-based studies analyzing the incidence and survival of SSM are limited. This retrospective study was designed to evaluate demographic factors influencing the incidence and survival of SSM using a national population-based database. The United States National Cancer Institute's Surveillance, Epidemiology, and End Results registry was used to calculate incidence and disease-specific survival trends for SSM between 1973 and 2012. Patient data were stratified according to age, sex, race, ulceration, thickness, and stage. Of 97 702 patients, 52.66% were men, 94.93% were white, and 38.92% had a primary lesion on the trunk. The overall incidence is 5.987/100 000 and is increasing with an annual percentage change (APC) of 1.42%. Incidence increases with age, peaking at 70-79 years. Men (6.68/100 00, APC: 1.78) had a significantly higher incidence than women (5.565/100 000, APC: 1.10). A total of 79.16% of SSM are less than or equal to 1 mm and 92.32% are nonulcerated. The overall 5-year survival is 95.30% and is increasing steadily. Women (hazard ratio: 0.54), 'other' races (hazard ratio: 0.30), those with local disease, those with thin tumors, and those without ulceration had higher survival than their counterparts (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|