Organ Doses from Radiation Therapy in Atomic Bomb Survivors
| Autor: | Akio A. Awa, Kazunori Kodama, Yasuyuki Fujita, Kenshi Komatsu, Kazuo Kato, Shigetoshi Antoku, Sachiko Kawamura |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Chromosome Aberrations
education.field_of_study Radiation Survival Life span business.industry medicine.medical_treatment Population Biophysics Cancer Radiotherapy Dosage medicine.disease Thermoluminescence Therapeutic radiation Radiation therapy medicine Humans Dosimetry Radiology Nuclear Medicine and imaging Thermoluminescence dosimetry education Nuclear medicine business Nuclear Warfare |
| Zdroj: | Radiation Research. 155:785-795 |
| ISSN: | 1938-5404 0033-7587 |
| DOI: | 10.1667/0033-7587(2001)155[0785:odfrti]2.0.co;2 |
| Popis: | Previous surveys of radiation therapy among the Life Span Study (LSS) population at the Radiation Effects Research Foundation (RERF) revealed that 1,670 (1.4%) of the LSS participants received radiation treatments before 1984. The data on therapeutic radiation doses are indispensable for studying the relationship between radiation treatments and subsequent cancer occurrences. In this study, the radiation treatments were reproduced experimentally to determine the scattered radiation doses. The experiments were conducted using a female human phantom and various radiation sources, including a medium-voltage X-ray machine and a (60)Co gamma-ray source. Doses were measured using thermoluminescence dosimetry and ionization chambers. Radiation doses were determined for the salivary glands, thyroid gland, breast, lung, stomach, colon, ovary and active bone marrow. The results have been used for documenting the organ doses received by patients in previous surveys. The contribution of therapeutic irradiation to the occurrence of chromosome aberrations was studied using data on doses to active bone marrow from both radiation treatments and atomic bomb exposures in 26 RERF Adult Health Study participants. The results suggest that radiation treatments contributed to a large part of their frequencies of stable-type chromosome aberrations. The therapeutic radiation doses determined in the present study are available for investigating the effects of therapeutic irradiation on the subsequent primary cancers among atomic bomb survivors who received radiation treatments. |
| Databáze: | OpenAIRE |
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