Women with breast cancer report substantially more disease- and treatment-related side or late effects than registered by clinical oncologists: a cross-sectional study of a standard follow-up program in an oncological department
| Autor: | Cai Grau, Anders Bonde Jensen, Mai-Britt Bjørklund Ellegaard, Robert Zachariae |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Cross-sectional study Outpatient clinic Aftercare Breast Neoplasms Disease Medical Oncology 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Surveys and Questionnaires Recurrent disease medicine Humans 030212 general & internal medicine Side effects Aged Aged 80 and over Sleep disorder business.industry Follow-up Late effects Loco-regional neoplasm recurrence Middle Aged medicine.disease Surgery Cross-Sectional Studies Oncology 030220 oncology & carcinogenesis Female Neoplasm Recurrence Local Breast neoplasms business Psychosocial After treatment |
| Zdroj: | Ellegaard, M B B, Grau, C, Zachariae, R & Jensen, A B 2017, ' Women with breast cancer report substantially more disease-and treatment-related side or late effects than registered by clinical oncologists: a cross-sectional study of a standard follow-up program in an oncological department ', Breast Cancer Research and Treatment, vol. 164, no. 3, pp. 727-736 . https://doi.org/10.1007/s10549-017-4301-x |
| Popis: | BACKGROUND: Follow-up after breast cancer treatment is standard due to the risk of development of new primary cancers and recurrent disease. The aim of the present study was to evaluate a standard follow-up program in an oncological department by assessing: (1) Symptoms or signs of new primary cancer or recurrent disease, (2) Disease- and treatment-related physical and psychosocial side or late effects, and (3) relevant actions by oncology staff. MATERIALS AND METHODS: In a cross-sectional study, 194 women who came for follow-up visit after treatment for primary surgery were included. The clinical oncologists registered symptoms and signs of recurrent disease or new primary cancer. Side or late effects were both assessed by patient and the clinical oncologists. RESULTS: Loco-regional or distant signs of recurrent disease were suspected in eight (5%) patients. Further examinations revealed no disease recurrence. Most patients (93%) reported some degree of side or late effects. Statistically significant more side or late effects were reported by the women (average: 6.9) than registered by the clinical oncologists (average: 2.4), p < 0.001. The three most often patient-reported side or late effects were hot flushes (35%), fatigue (32%), and sleep disturbance (31%). CONCLUSION: None of the scheduled or additional visits resulted in detection of recurrent disease. Furthermore, the majority of patients reported side or late effects. Statistically significant more women reported side or late effects than registered by the clinical oncologists. This suggests the need for rethinking of the follow-up programs with more emphasis upon side or late effects of the treatment. |
| Databáze: | OpenAIRE |
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